Program

This lecture will be at the Eduaction building of the LUMC.

18.30h Registration

19.00h Opening lecture by Prof.dr. Frans Claas

His-stoRI: Reproductive Immunology and Immunogenetics at a glance

Prof.dr. Frans Claas is emeritus professor “Immunogenetics of transplantation” at the Leiden University Medical Center in Leiden, the Netherlands. The main topics of his research are the differential immunogenicity of HLA mismatches in clinical transplantation and the immunology of pregnancy as a model for transplantation tolerance. The studies of his research group have generated more than 700 papers in peer-reviewed journals. He was the initiator of a very successful program within Eurotransplant to enhance transplantation of highly sensitised renal transplant patients on basis of acceptable HLA mismatches.

19.45h Drinks

NEW METHODS AND TOOLS IN REPRODUCTIVE IMMUNOLOGY

08:30 Key note Utilizing primary HLA-G+ EVT and EVT-like cell lines to study maternal-fetal interactions Tamara Tilburgs

08:55 Tissue-Specific Immune Variation and Reconstitution in the Human Uterus Niklas Bjorkstrom

09:20 Lactobacillus crispatus Surface Layer Proteins, multifaceted players of women’s health Alexiane Decout

09:45 Oral – abstract

10:00 Oral – abstract

10:15 Oral – abstract

10:30 Coffee

AUTO-IMMUNE OR AUTO INFLAMMATORY DISEASES AND REPRODUCTION

11:00 Key note Auto-immune or Auto-inflammatory Diseases, and Reproduction Lee Nelson

11:25 Scleroderma Marie-Pierre Piccinni

11:50 Fetomaternal immunity and rheumatoid arthritis Nathalie Lambert 

12:15 Oral – abstract

12:30 Oral – abstract

12:45 Oral – abstract

13:00 Lunch

PREECLAMPSIA: IMMUNOLOGIC ETIOLOGY AND BIOMARKERS OF OUTCOME

14:00 Preeclampsia Mark Spaanderman

14:25 Preeclampsia, fetomaternal immunization and cardiovascular risk Annetine Staff

14:50 Role of galectins in feto-maternal tolerance and metabolism Sandra Blois

15:15 Pre eclampsia Dorien Feyaerts

15:40 Coffee/tea

16:00 Poster session

MATERNAL-FETAL EXCHANGE, INTERACTION, AND CLINICAL IMPLICATIONS

16:45 In vitro placenta cell transfer model / role of exosomes Udo Markert

17:10 Fetal and neonatal alloimmune thrombocytopenia Joanne Verweij

17:35 uNK/trophoblast organoids/interaction/cytokines Ashley Moffett

Evening: Social program featuring a Surprise Act!

MALE REPRODUCTIVE IMMUNOLOGY, ENDOMETRIAL IMMUNITY, AND IMPLANTATION FAILURE

08.30 Immunological aspects of male infertility Jean-Pierre Allam

08:55 TBA Katerina Komrskova

09.20 : Endometrial immune profiling and targeted therapy increase live birth rate after embryo transfer Nathalie Ledée

09:45 Oral – abstract

10:00 Oral – abstract

10:15 Oral – abstract

10:30 Coffee

BEST ABSTRACT SESSION – ORAL PRESENTATIONS

11:00 Oral – best abstract

11:15 Oral – best abstract

11:30 Oral – best abstract

11:45 Oral – best abstract

BEST POSTER SESSION – ORAL PITCH PRESENTATIONS

12:00 Oral – best poster

12:05 Oral – best poster

12:10 Oral – best poster

12:15 Oral – best poster

12:30 Lunch

PRECONCEPTIONAL IMMUNOLOGICAL CHALLENGES

14:00 Key note Menstrual Effluent Analysis: Emerging Insights into Endometriosis Diagnosis and Treatment Christine Metz

14:25 Receptivity test Sam Schoenmakers

14:50 Oral – abstract

15:05 Oral – abstract

15:20 Oral – abstract

16:00 Coffee

PLACENTA MORPHOLOGY AND INFLAMMATION

16:30 Placental inflammatory syndromes David Williams

16:55 Placental pathology Lotte van der Meeren

17:20 3D organoid cultures to model cellular interactions in early human placentation Sandra Haider

17:45 Oral – abstract

18:00 Oral – abstract

18:15 Oral – abstract

19:00 Conference Dinner + Awards

RECURRENT PREGNANCY LOSS: IMMUNOLOGICAL ETIOLOGY AND IMMUNOTHERAPY 

09:00 Immunology in recurrent pregnancy loss Siobhan Quenby

09:25 Science in recurrent pregnancy loss Lisa Lashley

09:50 Lifestyle and recurrent pregnancy loss Tess Meuleman

10:15 Oral – abstract

10:30 Coffee/tea

PRETERM BIRTH AND IMMUNOLOGY

11:10 Adverse neonatal outcomes following antenatal infection and mechanical ventilation in preterm born lambs; charting paths for cell based interventions Tim Wolfs

11:35 Single-cell proteomic and transcriptomic immune signatures preceding spontaneous preterm birth Ina Stelzer

12:00 Oral- abstract

12:15 Oral – abstract

12:30 Oral – abstract

12:45 Oral – abstract

13:00 Lunch

TRANSFER OF IMMUNITY AND PATHOGENS TO THE FETUS

14:00 Prince study (passive immunity of immunoglobulins) Petra Arck

14:25 Maternal vaccination: the role of the placenta in antibody transfer and the impact of maternal pertussis immunisation on neonatal early-life immune responses Beth Holder

14:50 The maternal gut microbiome in pregnancy: implications for the developing immune system Marta Selma-Royo

15:30 Thank you and good-bye